风湿免疫性疾病患者的院内感染因素分析及对策

Analysis and countermeasures of nosocomial infection in patients with rheumatic immune diseases

目的:探讨风湿免疫性疾病患者发生院内感染的危险因素与应对策略。方法:收集2019年1月—2021年11月收治的4903例住院患者的临床资料,分析发生院内感染的情况与危险因素。结果:4903例风湿免疫性疾病患者中,发生院内感染者48例,发生率为0.98%,最常见的感染部位为下呼吸道感染(占41.7%),最常见的病原菌为大肠埃希菌(占31.6%)。经过分析发现年龄、住院天数、教育程度、侵入操作、使用激素/免疫抑制剂、淋巴细胞计数减少是院内感染的危险因素。结论:明确风湿免疫疾病患者院内感染的危险因素,能够有针对性地提升院内感染控制方案的可行性和实效性。

Objective:To explore the risk factors and countermeasures of nosocomial infection in patients with rheumatic immune diseases.Methods:The clinical data of 4903 inpatients admitted to the rheumatology department from January in 2019 to November in 2021 were retrospectively analyzed,and the situation and risk factors of nosocomial infection were investigated.Results:Among the 4903 patients with rheumatic immune diseases analyzed in this study,there were 48 patients with nosocomial infection,with an incidence of 0.98%.The most common infection site was lower respiratory tract infection(41.7%),and the most common pathogen was Escherichia coli(31.6%).Age,inpatient days,education level,invasive procedures,use of immunosuppressants/hormones,and reduced lymphocyte count were found to be risk factors for nosocomial infection.Conclusion:To clarify the risk factors of nosocomial infection in patients with rheumatic immune diseases,it is more targeted to improve the feasibility and effectiveness of nosocomial infection control programs.