摘要
目的探讨子宫内膜息肉(EP)复发的因素及预测价值。方法选取94例接受宫腔镜手术治疗的EP患者,根据患者术后是否复发分为复发组及非复发组,比较两组的一般资料,应用多因素Logistic回归分析EP患者复发的影响因素,应用受试者工作特征曲线,建立EP复发的预测模型,分析EP复发因素的预测价值。结果本组94例EP患者术后复发15例,复发率为15.96%;经单因素分析得出,年龄≥40岁、子宫内膜息肉病史、术后未使用避孕药是EP患者术后复发的影响因素(P<0.05);多因素Logistic回归分析显示,年龄≥40岁、子宫内膜息肉病史、术后未使用避孕药是EP患者术后复发的独立危险因素(P<0.05),子宫内膜息肉病史是患者术后复发的高危因素,术后使用避孕药是术后复发的保护因素;EP术后复发指数方程=0.314X1+0.275X2+0.306X3,指数越大术后复发的风险越高;术后未使用避孕药及子宫内膜息肉病史预测EP复发的AUC分别为0.754、0.779,说明两组因素对预测EP复发具有一定的效能。两项指标联合预测是AUC达到0.896。结论子宫内膜息肉病史及术后未应用避孕药是EP术后复发的危险因素,两组预测EP复发的效能较高,联合应用预测效能更佳。因此对于预防EP的复发,特别是既往有EP病史患者,术后给予联合药物治疗,从而减少EP的复发。
Objective To investigate the recurrence factors of endometrial polyp(EP)and its predictive value.Methods 94 patients with EP who underwent hysteroscopic surgery were selected and divided into relapse group and nonrecurrence group according to whether the patients relapsed after surgery.General data of the two groups were compared,multivariate Logistic regression was applied to analyze the influencing factors of relapse in EP patients,and the predictive model of EP recurrence was established by applying the subject work characteristic curve to analyze the predictive value of EP recurrence factors.Results In this group,15 of 94 EP patients had postoperative recurrence,with a recurrence rate of 15.96%.Univariate analysis showed that age≥40 years old,history of endometrial polyps and no use of contraceptives after surgery were the influencing factors for postoperative recurrence of EP patients(P<0.05).Multivariate Logistic review showed that age≥40 years old,history of endometrial polyps and no use of contraceptives after surgery were independent risk factors for postoperative recurrence in EP patients(P<0.05),history of endometrial polyps was a high risk factor for postoperative recurrence,and use of contraceptives after surgery was a protective factor for postoperative recurrence.EP recurrence index equation=0.314X1+0.275X2+0.306X3,the greater the index,the higher the risk of postoperative recurrence.The AUC values for predicting EP recurrence were 0.754 and 0.779,respectively,indicating that the two groups of factors were effective in predicting EP recurrence.The combined forecast is for an AUC of 0.896.Conclusion History of endometrial polyps and no use of contraceptives after surgery were risk factors for EP recurrence.The two groups had higher predictive efficacy for EP recurrence,and the combined application had better predictive efficacy.Therefore,for preventing the recurrence of EP,especially for patients with a history of EP,postoperative combined drug therapy should be given to reduce the recurrence of EP.
作者
望烨昕
刘君
何惠嫦
王晶晶
韩燕华
Wang Yexin;Liu Jun;He Huichang;Wang Jingjing;Han Yanhua(Department of Gynecology,Zhongshan People's Hospital,Zhongshan 528400,China)
出处
《实用妇科内分泌电子杂志》
2023年第7期1-5,共5页
Electronic Journal of Practical Gynecological Endocrinology
基金
中山市医学科研项目(编号2020A020525)。
关键词
子宫内膜息肉
复发
影响因素
预测模型
Endometrial polyp
Relapse
Influencing factors
Prediction model