子宫瘢痕憩室及宫腔积液对体外受精-胚胎移植妊娠结局的影响

Effect of uterine cicatricial diverticulum and uterine effusion on pregnancy outcome of in vitro fertilization-embryo transfer

目的探究观察子宫瘢痕憩室及宫腔积液对体外受精-胚胎移植妊娠结局的影响。方法选取84例体外受精-胚胎移植手术患者为研究对象,结合是否发生子宫瘢痕憩室、宫腔积液分组,其中子宫瘢痕憩室组(15例)、宫腔积液组(18例)、疾病合并组(10例)、健康正常组(41例)。四组患者均经体外受精-胚胎移植手术成功妊娠,统计四组的妊娠结局与分娩方式。结果四组的流产率比较,子宫瘢痕憩室组、疾病合并组最大,宫腔积液组次之,健康正常组最小,差异有统计学意义(P<0.05);四组的活产率比较,健康正常组最大、宫腔积液组次之,子宫瘢痕憩室组再次之,疾病合并组最小,差异有统计学意义(P<0.05);四组的经阴道分娩率比较,健康正常组大,宫腔积液组次之,子宫瘢痕憩室组、疾病合并组最小,差异有统计学意义(P<0.05)。结论子宫瘢痕憩室及宫腔积液会对体外受精-胚胎移植患者的妊娠结局、分娩方式造成影响,临床需高度重视,及时采用有效措施干预。

Objective To explore the effect of uterine scar diverticulum and uterine effusion on the pregnancy outcome of IVF and embryo transfer.Methods 84 patients with in vitro fertilization-embryo transfer surgery were selected as the study objects,and divided into groups based on whether uterine scar diverticulum and uterine effusion occurred,including uterine scar diverticulum group(15 cases),uterine effusion group(18 cases),disease combined group(10 cases),and healthy normal group(41 cases).All the patients in the four groups were successfully pregnant by in vitro fertilization-embryo transfer operation.The pregnancy outcome and delivery mode of the four groups were analyzed.Results Compared with the four groups,the abortion rate of uterine scar diverticulum group and disease combined group was the largest,followed by uterine effusion group,and the smallest in healthy and normal group,the difference was statistically significant(P<0.05).The live birth rate of the four groups was the highest in the healthy and normal group,followed by the uterine effusion group,followed by the uterine scar diverticulum group,and the lowest in the disease complicated group,with statistical significance(P<0.05).The vaginal delivery rate of the four groups was higher in the healthy and normal group,followed by the uterine effusion group,and the least in the uterine scar diverticulum group and the disease combined group,with statistical significance(P<0.05).Conclusion Uterine scar diverticulum and intrauterine effusion can affect the pregnancy outcome and delivery mode of patients with in vitro fertilization-embryo transfer,which requires high attention and timely intervention by effective measures.