老年女性糖尿病患者并发重症社区获得性肺炎预后的影响因素分析

Analysis of influencing factors of prognosis in elderly female diabetes patients complicated with severe community acquired pneumonia

目的分析老年女性糖尿病患者并发重症社区获得性肺炎(SCAP)预后的影响因素。方法选取2019年1月至2022年12月在泰安市中医二院重症监护室的100例糖尿病并发SCAP的老年女性患者作为研究对象,根据预后情况分为死亡组(n=30),生存组(n=70)。单因素及多因素logistic回归分析老年女性糖尿病患者并发SCAP预后的影响因素。结果单因素分析结果显示,老年女性糖尿病并发SCAP的预后与年龄、合并其他疾病、空腹血糖、糖化血红蛋白、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、血小板压积(PCT)有关(P<0.05)。logistic回归分析结果显示,年龄、合并其他疾病、空腹血糖、糖化血红蛋白、IL-6、TNF-α、CRP、PCT是影响老年女性糖尿病并发SCAP预后的独立危险因素(P<0.05)。结论年龄、合并其他疾病、空腹血糖、糖化血红蛋白、IL-6、TNF-α、CRP、PCT是影响老年女性糖尿病并发SCAP预后的独立危险因素,临床应根据以上因素进行防治,以改善其预后。

Objective To analyze of influencing factors of prognosis in elderly female diabetes patients complicated with severe community acquired pneumonia(SCAP).Methods A total of 100 elderly female patients with diabetes complicated with SCAP in the Intensive Care Unit of the Tai’an Second Hospital of Traditional Chinese Medicine from January 2019 to December 2022 were selected as the research objects.According to the prognosis,they were divided into the death group(n=30)and the survival group(n=70).Univariate and multivariate logistic regression analysis were used to analyze the influencing factors of prognosis in elderly female diabetic patients with SCAP.Results Univariate analysis showed that age,combined with other diseases,fasting blood glucose,glycosylated hemoglobin,interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)and plateletcrit(PCT)were related to the prognosis of elderly female diabetes complicated with SCAP(P<0.05).The results of logistic regression analysis showed that age,combined with other diseases,fasting blood glucose,glycosylated hemoglobin,IL-6,TNF-α,CRP and PCT were independent risk factors for the prognosis of elderly female diabetes complicated with SCAP(P<0.05).Conclusion Age,combined with other diseases,fasting blood glucose,glycosylated hemoglobin,IL-6,TNF-α,CRP and PCT are independent risk factors for the prognosis of elderly female diabetes complicated with SCAP.Clinical prevention and treatment should be taken according to the above factors to improve the prognosis.