双黄连制剂及其药物组成对大肠杆菌和金黄色葡萄球菌体外抑菌效果研究进展

Research Progress of Bacteriostatic Effect of Shuanghuanglian Preparation andIts Compositions on Escherichia coli and Staphylococcus aureus in vitro

双黄连是由黄芩、金银花与连翘组成的中药制剂,具有辛凉解表,清热解毒的功效。为进一步了解双黄连制剂及其药物组成对大肠杆菌和金黄色葡萄球菌各自的药理作用及抑菌效果,本文将从药理作用机制、体外抑菌效果研究、影响药物体外抗菌活性的因素等方面进行综述,以期为双黄连制剂的综合疗效、与抗菌药物的联合使用和配方颗粒的临床应用等后续研究工作的深入开展提供参考。

Shuanghuanglian is a traditional Chinese medicine preparation composed of scutellaria scutellaria,honeysuckle and forsythia.It has the functions of cooling,clearing heat and detoxifying.In order to further understand the pharmacological actions and antibacterial effect of Shuanghuanglian preparation and tis compositions on Escherichia coli and Staphylococcus aureus,the pharmacological mechanism,antibacterial effect in vitro and factors affecting the antibacterial activity of the drugs were reviewed in this paper to provide reference for further research on the comprehensive effect of Shuanghuanglian preparation,the combined use of antibacterial drugs and the clinical application of formula particles.