乳腺癌保乳术后调强放疗影像引导技术的研究进展

Research progress on image-guided radiotherapy after breast-conserving surgery for breast cancer

乳腺癌保乳术后调强放疗可出现摆位误差,由此可增加放射性损伤,引起放射性心脏病或放射性肺炎,甚至导致肿瘤控制失败。随着影像引导放疗技术(IGRT)的发展,多种影像引导技术已广泛用于临床以解决放疗过程中各种摆位误差,包括二维X线影像引导、三维X线影像引导、MR影像引导、光学体表引导等技术。就多种影像引导技术在乳腺癌保乳术后调强放疗中的应用进展及优缺点作一综述。

Intensity-modulated radiotherapy(IMRT)following breast-conserving surgery can be associated with positional errors that may increase the risk of radiation-induced complications such as radiation heart disease,radiation pneumonia,and compromised tumor control.To address these challenges,image-guided radiotherapy technology(IGRT)has been developed and various image guidance techniques have been implemented in clinical practice.These techniques include 2D X-ray image guidance,3D X-ray image guidance,MR image guidance,optical body guidance,and other approaches.We reviews the progress,advantages,and limitations of these image-guided techniques in the application of IMRT after breast-conserving surgery for breast cancer.