中医干预乳腺癌内分泌治疗后失眠的临床研究近况

Clinical research progress of traditional Chinese medicine on insomnia after endocrine therapy for breast cancer

内分泌治疗是雌激素受体和(或)孕激素受体阳性乳腺癌患者的重要治疗方法,其中失眠是治疗后常见的不良反应之一,严重影响了患者的生活质量。文章从中医病名、病因病机及治法等方面对乳腺癌内分泌治疗后失眠的研究近况进行综述,介绍了近年来中医药治疗乳腺癌内分泌治疗后失眠的研究进展,旨在通过综述为乳腺癌失眠的临床治疗提供理论依据与指导。乳腺癌内分泌后失眠的基本病机为肾虚毒蕴,中医药干预的常用治法包括中药方剂疗法、针刺疗法、针药联合疗法、穴位贴敷疗法、推拿法及芳香疗法等,这些疗法安全、经济,且内外兼顾,具有疗效显著、依从性高及不良反应少的优点。

Endocrine therapy is an important treatment for patients with estrogen receptor and/or progesterone receptor positive breast cancer,in which insomnia is one of the common adverse effects after treatment,which seriously affects the quality of life of patients.This paper presents the research progress of Chinese medicine in the treatment of insomnia after endocrine therapy for breast cancer in recent years,aiming to provide theoretical basis and guidance for the clinical treatment of insomnia in breast cancer through a review.A review of recent research on insomnia after endocrine therapy for breast cancer in terms of Chinese medical names,etiology and treatment.The basic pathogenesis of insomnia after endocrine breast cancer is“kidney deficiency and toxicity”.The common treatments of traditional Chinese medicine intervention include Chinese herbal prescription therapy,acupuncture therapy,combined acupuncture and medicine therapy,acupuncture point application therapy,massage and aromatherapy,etc.These treatments are safe,economical,and have significant efficacy both inside and outside.Chinese medicine uses multiple modalities to intervene in insomnia after endocrine therapy for breast cancer,which has the advantages of good efficacy,high compliance and few side effects.