胼胝体解剖分区及孤独症谱系障碍胼胝体MRI的研究进展

Research progress of corpus callosum anatomic partitioning and MRI of corpus callosum in autism spectrum disorder

胼胝体(CC)是脑内最大的连接纤维,基于孤独症谱系障碍(ASD)的脑部连通障碍假说,CC异常可能会导致ASD相应的症状。目前ASD的发病率日益增加,但关于ASD的CC研究结果不一,且CC解剖分区及分析方法多样,故本文就ASD患儿CC的解剖分区方法、CC相关MRI技术及研究进展进行综述。

The corpus callosum(CC)is the largest connecting fiber in the brain,and based on the hypothesis of brain connectivity disorder of autism spectrum disorder(ASD),abnormal CC may lead to the corresponding symptoms of ASD.Currently,the incidence of ASD is increasing,but the results of CC studies on ASD are different,and CC anatomical partitioning and analysis methods are various.Therefore,this paper reviews the anatomical partitioning methods of CC,CC-related MRI techniques and research progress in ASD children.