肝硬化与肠道菌群相关性的知识图谱可视化分析

Visual analysis of knowledge map correlation between cirrhosis and gut microbiota

目的 肝硬化与肠道菌群相关性的知识图谱可视化分析。方法 采用VOSviewer和Cite Space对CNKI与1 000篇。中文作者有5个合作群,英文以Jasmohan S Bajaj团队为主;研究机构集中在高校及附属医院;高频关键词为益生菌、内毒素等,研究热点为肠道细菌移位、微生态制剂等。结论 知识图谱展现了肝硬化和肠道菌群的研究进程,重点呈现了微生物制剂、菌群代谢产物与肝硬化的关系,未来热点可能与防治肠道菌群失衡、探讨菌群移植的机制等有关。

Objective To analyze the relationship of cirrhosis and gut microbiota by text network analysis.Methods By using VOSviewer and CiteSpace,the author and institutional cooperation network,keywords and breakout words of the literatures collected by CNKI and WOS from January 1992 to June 2022 were analyzed.Results A total of 1000 articles were included.The Chinese author had five cooperative groups,and the English author was mainly Jasmohan S Bajaj team.Research institutions were concentrated in universities and affiliated hospitals;the high-frequency keywords were probiotics,endotoxins,etc.,and the research focused on intestinal bacterial translocation and microecological preparations.Conclusion The knowledge map shows the research progress of liver cirrhosis and intestinal flora,focusing on the relationship between microbial preparations,microbial metabolites and liver cirrhosis.Future hotspots may be related to preventing gut microbiota imbalance and exploring the mechanism of bacterial flora transplantation.