基于肠道菌群的运动干预慢性便秘可能机制的研究进展

Research progress on possible mechanism of exercise intervention in chronic constipation based on intestinal flora

慢性便秘(CC)的发病机制目前尚无明确定论,随着对肠道微生态研究的深入,肠道菌群及其代谢产物失衡被认为是CC的潜在诱发因素。运动作为CC治疗的基础措施之一,可以通过调节肠道微生物的组成参与机体代谢、抗炎、氧化应激等过程,提示肠道菌群、运动与CC之间存在某种内在联系。本文基于肠道菌群就运动改善CC的潜在作用机制进行了归纳及综述,以期为后续深入探究运动防治CC提供新思路。

The pathogenesis of chronic constipation(CC)is still not yet clearly established,and with the deepening of intestinal microecology research,the imbalance of intestinal flora and its metabolites is considered to be the potential predisposing factor of CC.Exercise as one of the basic measures of CC treatment,it can participate in metabolism,anti-inflammatory,oxidative stress,and other processes by regulating the composition of intestinal microorganisms,it is suggested that there is some internal relationship between intestinal flora,exercise,and CC.This paper summarizes and reviews the potential mechanism of exercise to improve CC based on intestinal flora,in order to provide new ideas for further exploration of exercise,prevention and treatment in CC.