基于CiteSpace的中医药治疗肾纤维化作用机制的可视化分析

Visual analysis of the mechanism of traditional Chinese medicine for renal fibrosisi based on CiteSpace

目的基于Citespace对中医药干预肾纤维化的作用机制进行可视化分析,探究该领域的研究热点。方法检索中国知网2001年1月至2022年10月收录的中医药治疗肾纤维化作用机制的文献,用Citespace对作者、机构和关键词进行分析生成一系列图谱。结果经人工筛选和软件去重后共纳入371篇文献,年度发文量整体呈上升趋势。核心作者13名,晏子友团队发文最多,机构以北京中医药大学发文量最多。益气活血化瘀类药物的使用和氧化应激、炎症、自噬等作用机制为研究热点。结论知识图谱直观展示出中医药干预肾纤维化作用机制方面研究热点的演变进程,为今后的工作提供参考。

Objective To visual analysis of the mechanism of traditional Chinese medicine intervention in renal fibrosis based on CiteSpace,and to explore research hotspots in this field.Methods The literatures on the mechanism of traditional Chinese medicine treatment of renal fibrosis collected on CNKI from January 2001 to October 2022 were retrieved.The authors,institutions,and keywords were analyzed by CiteSpace and generated a series of maps.Results After manual screening and software removal,371 literatures were included,and the annual publication volume showed an overall rising trend.Among the 13 core authors,Yan Ziyou’s team published the most papers,and Beijing University of Chinese Medicine published the most papers.The use of qi-enhancing and blood-activating drugs to remove blood stasis and the mechanism of oxidative stress,inflammation,and autophagy were hot topics of research.Conclusion Through the statistical atlases,the evolution process of research hotspots about the mechanism of intervention of traditional Chinese medicine on renal fibrosisi is visually displayed.The current work will provide some reference for future scientific research in this field.