微循环监测对脓毒性休克治疗的指导作用

The guiding role of microcirculation monitoring in the treatment of septic shock

脓毒性休克是脓毒症进展的最危重阶段,纠正组织低灌注是脓毒性休克治疗的核心,除液体复苏改善大循环外,还需要改善机体微循环,对不同类型休克应用相应的血管活性药物以满足机体对灌注的需求。脓毒性休克病情进展迅速,不同病理生理阶段微循环状态不同,增加了合理使用血管活性药物的难度。对外周微循环的监测和精准评估,对脓毒性休克的个体化治疗提供一定的指导作用。

Septic shock is the most critical stage of sepsis,and the core of the treatment is improving tissue hypoperfusion.In addition to the improvement of large circulation by fluid resuscitation,the microcirculation also need to be improved,then proper vasoactive drugs should be applied to different types of shock to meet the needs of the body for perfusion.The condition of septic shock progresses rapidly,and the microcirculation in different pathophysiological stages is different,which increases the difficulty of rational use of vasoactive drugs.Monitoring and accurate evaluation of peripheral microcirculation may provide guidance for individualized treatment of septic shock.