摘要
To investigate the impact of the fixed latent periods in the human and vector populations on the disease transmission in heterogenous environment,we formulate a nonlocal and time-delayed reaction-diffusion(NLTD-RD)system.By appealing to the next generation operator(NGO),we define the basic reproduction number(BRN)Ro,and prove it as a threshold parameter for indicating whether disease persists or not.Specifically,if o<1,the disease-free equilibrium is globally asymptotically stable,while if Ro>1,the disease is shown to be uniformly persistent.In the homogeneous case that all parameters are assumed to be constants,the explicit expression of o is obtained.We further achieved the global attractivity of the constant equilibria by utilizing Lyapunov functionals.Numerical simulations are performed to verify the theoretical results and the effects of the diffusion rate on disease transmission.
基金
supported by National Natural Science Foundation of China(Nos.12071115 and 11871179)
Fundamental Research Funds for the Universities in Heilongjiang Province(No.2021-KYYWF-0017)
Heilongjiang Provincial Key Laboratory of the Theory and Computation of Complex Systems.