超敏C反应蛋白、血脂指标检验结果对糖尿病新发患者的评估研究

Evaluation Study of Test Results of High-Sensitivity C-Reactive Protein and Blood Fat Index in Patients with New-onset Diabetes

目的研究超敏C反应蛋白(hs-CRP)、血脂指标检验结果用于评估糖尿病(diabetic mellitus,DM)新发患者的临床价值。方法选取2022年1月—2023年1月湖北省枣阳市中医医院医学检验科收入的健康体检人员64名作为对照组,同期收入的糖尿病新发患者64例作为研究组,两组均进行血糖、超敏C反应蛋白(hsCRP)与血脂指标检测,对比分析两组血糖指标、超敏C反应蛋白及血脂指标水平。结果研究组空腹血糖(FPG)、餐后2 h血糖(2 hPG)以及糖化血红蛋白(HbA1c)水平均较对照组高,差异有统计学意义(P<0.05);研究组血清hs-CRP、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)以及总胆固醇(TC)水平高于对照组,高密度脂蛋白(HDL-C)低于对照组,差异有统计学意义(P<0.05)。结论在糖尿病新发患者的疾病诊断中,除血糖常规检测外,超敏C反应蛋白、血脂指标检验能够及时评估患者机体内部状况,为其疾病诊断与治疗提供更多参考依据,临床应用价值较高。

Objective To study the clinical value of the test results of high-sensitivity C-reactive protein(hs-CRP)and blood fat index in evaluating patients with new-onset diabetic mellitus(DM).Methods From January 2022 to January 2023,64 health examiners from the medical laboratory department of Zaoyang Hospital of Traditional Chinese Medicine in Hubei Province were selected as the control group,and 64 new diabetes patients from the same period were selected as the study group.Both groups were tested for blood glucose,hypersensitive C-reactive protein(hs CRP),and blood lipid indicators,and the levels of blood glucose,hs-CRP,and blood lipid indicators were compared and analyzed between the two groups.Results The levels of fasting plasma glucose(FPG),2 h postprandial plasma glucose(2 hPG)and glycated hemoglobin(HbA1c)in the study group were significantly higher than those in the control group,the difference was statistically significant(P<0.05).The levels of hs CRP,low-density lipoprotein cholesteroled(LDL-C),triacylglycerol(TG)and total cholesterol(TC)in the study group were higher than those in the control group,while high-density lipoprotein cholesteroled(HDL-C)was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion In the disease diagnosis of patients with new-onset diabetes,in addition to the routine blood glucose detection,the tests of high-sensitivity C-reactive protein and blood fat index can timely evaluate the internal inflammatory status of patients,providing more reference for the disease diagnosis and treatment.Moreover,its clinical application value is high.