急性缺血性脑卒中患者赋权水平、药物素养与二级预防用药依从性的相关性研究

Correlation between empowerment level,drug literacy and compliance of secondary preventive drugs in patients with acute ischemic stroke

目的了解急性缺血性脑卒中(AIS)患者二级预防用药依从性现状,并分析用药依从性与赋权水平、药物素养之间的相关性。方法选取我院2019年1月-2022年9月收治的287例AIS患者作为研究对象,采用一般资料调查表、Morisky服药依从性问卷、中文版健康赋权量表和药物素养量表对其进行问卷调查;采用单因素和Logistic回归分析筛选二级预防用药依从性的危险因素;采用Pearson分析二级预防用药依从性与赋权水平、药物素养之间的相关性。结果本组AIS患者用药依从性总分为(6.37±0.55)分,赋权水平总分为(28.52±3.38)分,药物素养总分为(4.58±0.32)分;年龄≥60岁、初中以下文化程度、家庭月收入≤5000元、药物不良反应经历是AIS患者用药依从性差的独立危险因素(P<0.05);AIS患者用药依从性与药物素养、赋权水平均呈正相关(P<0.05)。结论AIS患者用药依从性与药物素养、赋权水平评分均处于中等水平,且用药依从性与药物素养、赋权水平均呈正相关。临床工作人员应关注AIS患者药物素养、赋权水平,针对性地采取措施以提高二级预防用药依从性。

Objective To understand the current status of medication adherence of secondary prevention drugs in patients with acute ischemic stroke(AIS)and to analyze the correlation between medication adherence and empowerment level and drug literacy.Methods A total of 287 patients with AIS admitted to our hospital from January 2019 to September 2022 were selected as the study subjects,and they were investigated using the general information questionnaire,Morisky Medication Adherence Questionnaire and Chinese version of Health Empowerment Scale and Drug Literacy Scale;risk factors for secondary prevention medication adherence were screened using univariate and Logistic regression analysis;the correlation between secondary prevention medication adherence and empowerment level and drug literacy was analyzed by Pearson.Results The total medication adherence score of AIS patients in this group was 6.37±0.55,the total empowerment level score was 28.52±3.38,and the total drug literacy score was 4.58±0.32;age≥60 years,education level below junior high school,monthly household income≤5000 yuan,and experience of adverse drug reactions were independent risk factors for poor medication adherence in AIS patients(P<0.05);medication adherence of AIS patients was positively correlated with drug literacy and empowerment level(P<0.05).Conclusion Medication adherence,drug literacy and empowerment level scores of AIS patients were all at moderate levels,and medication adherence was positively correlated with drug literacy and empowerment level.Clinical staff should pay attention to the medication literacy and empowerment level of AIS patients and take targeted measures to improve the medication adherence of secondary prevention drugs.