期刊文献+

西门塔尔牛常见遗传缺陷及其分子机制研究进展 被引量:1

Advances in the Common Genetic Defects and Their Molecular Mechanisms in Simmental Cattle
下载PDF
导出
摘要 西门塔尔牛是生产性能优良且适应性强的乳肉兼用型牛品种。近年来,随着基因组检测芯片和全基因组测序技术的应用,国内外学者在西门塔尔牛中鉴定出多种新的遗传缺陷。本文综述了西门塔尔牛13种遗传缺陷的表型特征及分子机制研究进展,提示我国在引种和遗传改良过程中进行科学有效的遗传缺陷风险管理的必要性,也为我国牛育种中有害基因的准确筛查和逐步淘汰提供了科学资料。 Simmental cattle is a milk-meat dual-purpose cattle breed with outstanding production performance,roughage tolerance and strong disease resistance.In recent years,with the application of genomic SNP chip and whole genome sequencing technology,scientists have identified a number of new genetic defects in Simmental cattle.This paper reviews the phenotypic characteristics and molecular mechanisms of 13 genetic defects reported in Simmental cattle,which highlights the importance of genetic risk management and mating program development and provides scientific data for diagnosis and genetic management of these harmful genes in cattle breeding in China.
作者 张可 欧四海 司敬方 杨阳 赵宗胜 赵康 许维 柳咏雪 王雅春 张毅 ZHANG Ke;OU Sihai;SI Jingfang;YANG Yang;ZHAO Zongsheng;ZHAOKang;XU Wei;LIU Yongxue;WANG Yachun;ZHANG Yi(College of Animal Science and Technology,China Agricultural University,Beijing 100193,China;Shihezi Animal Husbandry and Veterinary Workstation,The Eighth Division of Xinjiang Production and Construction Corps,Xinjiang Shihezi 832000,China;College of Animal Science and Technology,Shihezi University,Xinjiang Shihezi 832000,China;Tianjin Jialihe Livestock Production Corps,Tianjin 300409,China)
出处 《中国畜牧杂志》 CAS CSCD 北大核心 2023年第7期40-45,共6页 Chinese Journal of Animal Science
基金 新疆生产建设兵团科技计划项目(2021AA004) 财政部和农业农村部:国家现代农业产业技术体系(CARS36) 天津市科技计划项目(19ZXZYSN00130)。
关键词 西门塔尔牛 遗传缺陷 单倍型 隐性遗传 Simmental Genetic defect Haplotype Recessive inheritance
  • 相关文献

参考文献5

二级参考文献60

  • 1Rieck GW,Schade W.Arachnomelia (spider limes),a new hereditary fatal malformation syndrom of cattle.Dtsch Tierarztl Wochenschr,1975,82:342-347 (In German).
  • 2Konig H,Gaillard C,Chavaz J,HUnziker F,Tonitis A.Prufung von Schweizer Brunvich-bullen auf das vererbte syndrom der arachnomelie und arthrogrypose (SAA) durch untersuchung der nachkonmmen im fetalstadium.Tierarztl Umsch,1987,42:692-697.
  • 3Testoni S,Gentile A.Arachnomelia in four Italian Brown calves.Vet Rec,2004,155(12):372.
  • 4Drogemüller C,Rossi M,Gentile A,Testoni S,Stranzinger G,Drogemüller M,Glowatzki-Mullis ML,Leeb T.Arachnomelia in Brown Swiss cattle maps to chromosome 5.Mamm Genome,2009,20(1):53-59.
  • 5Buitkamp J,Lühn C,Semmer J,Gotz K.U.Assinment of the locus for arachnomelia syndrome to bovine chromosome 23 in Simmental cattle.Anim Genet,2009,40(6):894-899.
  • 6Brem G,Wanke R,Hondele J,Dahme E.Occurrence of the areachnomelia syndrome in Bavarian Brown-Swiss Braunvich breed population.Berl Munch Tierarztl Wochenschr,1984,97:393-397 (in German).
  • 7Drogemüller C,Tetens J,Sigurdsson S,Gentile A,Testoni S,Lindblad-Toh K,Leeb T.Identification of the bovine Arachnomelia mutation by massively parallel sequencing implicates sulfite oxidase(SUOX) in bone development.PLoS Genet,2010,6(8):1-7.
  • 8Beever JE,Smit MA,Meyers SN,Hadfield TS,Bottema C,Albretsen J,Cockett NE.A single-base change in the tyro-sine kinase II domain of ovine FGFR3 causes hereditary chondrodysplasia in sheep.Anim Genet,2006,37(1):66-71.
  • 9Cockett NE,Shay TL,Beever JE,Nielsen D,Albretsen J,Georges M,Peterson K,Stephens A,Vernon W,Ti-mofeevskaia O,South S,Mork J,Maciulis A,Bunch TD.Localization of the locus causing Spider Lamb Syndrome to the distal end of ovine Chromosome 6.Mamm Genome,1999,10(1):35-38.
  • 10Chen L,Li CL,Qiao WH,Xu XL,Deng CX.A Ser365-Cys mutation of fibroblast growth factor recptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.Hum Mol Genet,2001,10(5):457-465.

共引文献12

同被引文献15

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部