甲状腺超声和超声造影诊断甲状腺结节中的价值对比研究

Study on value of thyroid ultrasound and contrast-enhanced ultrasound in diagnosis of thyroid nodules

目的 探究甲状腺结节患者接受甲状腺超声与超声造影检查的临床诊断价值差异。方法 从周口市第三人民医院2013年1月至2018年12月收治的患者中抽选出200例甲状腺结节患者(221个结节)作为本次研究对象,所有患者均接受甲状腺超声与超声造影检查,以手术病理检查结果为金标准,对比甲状腺超声、超声造影的检查结果与诊断符合率差异;详细分析甲状腺超声与超声造影两种检查方式的图像表现。结果 200例(221个结节)患者经甲状腺超声检查,良性结节143例,恶性结节78例,误诊19例;200例(221个结节)患者经超声造影检查,良性结节144例,恶性结节77例,误诊8例。患者经超声造影诊断,特异度97.79%(141/144)、灵敏度93.51%(72/77)、诊断符合率96.38%(213/221),均强于甲状腺超声,χ^(2)=8.324,10.354,3.645,P<0.05。甲状腺患者从增强水平、增强形态、增强均匀性、增强后边界、增强模式及退出模式看,其差异均存在统计学意义,P<0.05。结论 相比于甲状腺超声,超声造影对甲状腺结节的检查,诊断价值较为理想,有助于判断患者甲状腺结节良恶性。

Objective To explore the difference of clinical value of thyroid ultrasound and contrast-enhanced ultrasound in detecting thyroid nodules.Methods Totally 200 patients with thyroid nodules diagnosed and treated in our hospital from January 2013 to December 2018 were taken as the study subjects,with a total of 221 nodules.The results of thyroid ultrasound and contrast-enhanced ultrasound were compared with the results of surgery and pathology.The pathological results were taken as the gold standard,and the diagnostic coincidence rate of the two methods was analyzed;the image performance of the two examination methods was compared.Results According to thyroid ultrasound,143 patients were benign,78 were malignant,and 19 were misdiagnosed;according to contrast-enhanced ultrasound,144 patients were benign,77 were malignant,and 8 were misdiagnosed.The specificity,sensitivity and diagnostic coincidence rate of contrast-enhanced ultrasound were 97.79%,93.51%and 96.38%respectively,which were significantly higher than those of thyroid ultrasound(P<0.05).Based on their image performance,there are significant differences in enhancement level,enhancement shape,enhancement uniformity,post enhancement boundary,enhancement mode and exit mode between the two,P<0.05.Conclusion Compared with the thyroid ultrasound,the diagnostic value of contrast-enhanced ultrasound is ideal,which is helpful to judge the benign and malignant thyroid nodules of patients.