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Enhancement of SARS-CoV-2 vaccine-induced immunity by a Toll-like receptor 7 agonist adjuvant

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摘要 Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an enveloped positive-sense single-stranded RNA(ssRNA)virus responsible for the global COVID-19 pandemic.Although vaccines for SARS-CoV-2 have been developed and applied worldwide,research on vaccine adjuvant is lacking.Viral infections normally elicit a range of innate immune responses through the activation of pattern recognition receptors(PRRs).
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2023年第6期2481-2484,共4页 信号转导与靶向治疗(英文)
基金 research funding from Guangzhou Women and Children Medical Center,the National Key Research and Development Program of China(2018YFA0107200) National Natural Science Foundation of China(81730005 and 31771616) Macao FDCT(FDCT 0106/2021/A)。
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