妇科恶性肿瘤术中三维重建技术与临床应用研究

Three-dimensional reconstruction technique and its clinical application in gynecological malignant tumor surgery

目的探讨在妇科恶性肿瘤疾病的手术治疗中应用三维重建技术辅助疾病治疗的价值。方法将2018年1月至2021年1月该院收治的卵巢癌患者80例采用随机数字表法分为研究组和对照组,每组40例。对照组应用经腹卵巢癌根治术治疗,研究组应用经腹卵巢癌根治术联合三维重建技术治疗,观察2组患者临床疗效。结果研究组患者手术时间比对照组长,术中出血量、淋巴结清扫数量、住院时间均少/短于对照组,随访1年复发率低于对照组,差异均有统计学意义(P<0.05);2组患者术后7 d血清基质金属蛋白酶-9、人附睾蛋白4、甲壳质酶蛋白40水平均较术前明显降低,且研究组患者术后7 d血清基质金属蛋白酶-9、人附睾蛋白4、甲壳质酶蛋白40水平均低于对照组,差异均有统计学意义(P<0.05);2组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论妇科卵巢癌根治术中应用三维重建技术辅助手术治疗的手术效果较好,术后恢复快,可明显下调血清肿瘤因子水平,降低术后并发症及复发率。

Objective To explore the value of three-dimensional reconstruction technology in the surgical treatment of gynecological malignant tumors.Methods From January 2018 to January 2021,A total of 80 patients with ovarian cancer admitted to this hospital were divided into the experimental group and the control group by random number table method,with 40 cases in each group.The control group was treated with transabdominal radical resection of ovarian cancer,and the experimental group was treated with transabdominal radical resection of ovarian cancer combined with three-dimensional reconstruction technology.The clinical efficacy of the two groups was observed.Results The operation time of the experimental group was longer than that of the control group.The amount of intraoperative blood loss,the number of lymph nodes dissected and length of hospital stay in the experimental group were less/shorter than those in the control group,and the differences were statistically significant(P<0.05).The serum levels of matrix metalloproteinase-9(MMP-9),human epididymal protein 4(HE4)and chitinase protein 40(YKL-40)in the experimental group were significantly lower than those in the control group at seven days after operation,with statistical significance(P<0.05).There was no significant difference in the incidence of postoperative complications between the two groups(P<0.05).Conclusion In radical resection of gynecological ovarian cancer,the application of three-dimensional reconstruction technology for surgical treatment has a good surgical effect,rapid postoperative recovery,and can significantly reduce the level of serum tumor factors,and reduce the postoperative complications and recurrence rate.