摘要
目的分析120例摩氏摩根菌的临床分布以及药敏情况,为临床提供用药参考依据。方法对120例摩氏摩根菌的临床分布以及药敏结果进行回顾性分析。结果摩氏摩根菌感染范围广,标本主要来源于尿液(40%)、痰液(29%)和创面分泌物(23%);科室分布以ICU和老年病科为主(均占18%),在泌尿科检出率也较高(13%);感染患者多数患有基础疾病,所检出的摩氏摩根菌对阿米卡星、厄他培南、头孢吡肟、哌拉西林/他唑巴坦、头孢曲松、氨曲南的敏感率较高(>80%);敏感性低于10%的抗生素有氨苄西林、头孢唑林、呋喃妥因、替加环素、阿莫西林/棒酸。结论摩氏摩根菌最常引起泌尿道感染,易感患有基础疾病的人群,治疗上推荐使用阿米卡星、厄他培南、头孢吡肟进行治疗。
Objective The clinical distribution and drug susceptibility of 120 cases of Morganella morganii were analyzed to provide clinical reference for clinical medicine use.Methods The clinical distribution and susceptibility results of 120 cases of Morganella morganii were retrospectively analyzed.Results Morganella morganii infection is widespread with specimens derived mainly from urine(40%),sputum(29%),and wound discharge(23%).The distribution of departments is mainly ICU and geriatrics(both accounting for 18%),and the detection rate in urology is also high(13%).Most infected patients have underlying medical conditions.The detected Morganella morganii had a high sensitivity rate(>80%)to amikacin,ertap⁃enem,cefepime,piperacillin/tazobactam,ceftriaxone,and aztreonam.Antibiotics less than 10%sensitivity are ampicillin,cefazolin,nitrofurantoin,tigecycline,amoxicillin/rodic acid.Conclusion Morganella morganii most commonly causes urinary tract infections and is susceptible to people with underlying diseases.Treatment with amikacin,ertapenem,and cefepime is recommended.
作者
石翯
闫涛
楼正青
SHI He;YAN Tao;LOU Zheng-qing(Medical Laboratory Center,Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University,Zhejiang 310007,China)
出处
《中国卫生检验杂志》
CAS
2023年第12期1449-1451,共3页
Chinese Journal of Health Laboratory Technology
关键词
摩氏摩根菌
耐药性
科室分布
尿路感染
创面感染
Morganella morganii
Drug resistance
Department distribution
Urinary tract infection
Wound infection