夜班轮班作业与心血管疾病的关系及其相关机制研究进展

Research progress on the relation and related mechanism of night shift work and cardiovascular disease

心血管疾病是一类涉及心脏或血管的疾病,每年因心血管疾病死亡的人数约占全球所有死亡人数的1/3。不健康饮食、缺乏身体活动、吸烟和过量饮酒等都是心血管疾病的危险因素。随着夜班轮班工人的数量不断增加,由此导致的心血管疾病患病人数不断增加,夜班轮班作业也逐渐成为心血管疾病的危险因素之一。目前,夜班轮班作业导致心血管疾病的发病机制尚不明确,本文归纳了夜班轮班作业与心血管疾病及相关生化指标的关系,并对相关机制的研究进行了总结。

Cardiovascular disease is a class of diseases involving the heart or blood vessels,which accounts for about one-third of all deaths worldwide each year.Unhealthy diet,lack of physical activity,smoking and excessive alcohol consumption are all risk factors for cardiovascular disease.With the increasing number of night shift workers,the number of patients with cardiovascular disease has increased,and night shift work has gradually become a risk factor of cardiovascular disease.At present,the mechanism of cardiovascular disease caused by night shift work is still unclear.This review summarizes the relationship between night shift work and cardiovascular disease and its related biochemical indicators,and discusses the research on related mechanisms.