硒及硒蛋白与帕金森病关系的研究进展

Progress on the relationship between selenium,selenium protein and Parkinson's disease

硒是人类健康必需的微量元素,主要以硒蛋白的形式发挥生物学效应,主要参与调节细胞氧化应激、免疫应答和炎症反应等生物过程。近年来的研究发现,硒蛋白可通过多种途径发挥抗氧化等作用参与帕金森病的发病机制。本文就硒及硒蛋白在帕金森病关系中的研究进展做一综述。

Selenium is an essential trace element for human health,which mainly exerts biological effects in the form of selenoprotein.The function of selenoprotein is primarily to regulate biological processes such as oxidative stress in cells,immune response,and inflammation in the body.In recent studies,selenoproteins have been found to play an antioxidant role in the pathogenesis of Parkinson's disease through a variety of mechanisms.The article reviews the progress on selenium and selenoproteins in Parkinson's disease.