江苏省南京市新报告HIV/AIDS感染及影响因素调查分析

Infection and its influencing factors of newly reported HIV/AIDS in Nanjing city,Jiangsu Province

目的了解江苏省南京市新报告艾滋病病毒感染者/患者(HIV/AIDS)的感染来源、感染时间并分析相关因素。方法招募2020年1月1日至2022年6月30日南京市新报告HIV/AIDS作为研究对象,利用个案溯源信息调查问卷收集其人口学特征、行为学特征、可能的感染来源和感染时间等信息。新近感染是指确证前1年内有HIV检测阴性史,或1.5年内有检测阴性史且最近1年内有高危行为,或首次CD4+T淋巴细胞≥500个/μL。结果1119名调查对象,本地感染病例占可判断感染地点研究对象的80.19%;新近感染的病例占全部研究对象的55.76%。多因素logistic分析结果显示,女性、高中/中专/职高学历、非学生人群、在南京居住时间半年以上、经男男同性性行为途径感染的人群是判定为本地感染的相关因素;≤24岁年龄组、已婚有配偶、初中以上学历、确诊前1年非婚性伴个数≥2个、确诊前曾接受HIV抗体检测、第一次发生性行为的年龄≥18岁是判定为新近感染的相关因素。结论2020—2022年南京市新报告HIV/AIDS以本地感染和新近感染为主,今后应重点干预在南京市本地感染风险较高人群,针对非新近感染人群特征制定检测发现策略,进一步提高早发现比例。

Objective To understand the source of infection,time of infection and related factors in newly reported HIV infection and AIDS patients.Methods The newly reported HIV/AIDS in Nanjing from January 1,2020 to June 30,2022 was recruited as research objects.Demographic characteristics,behavioral characteristics,possible sources of infection and time of infection were collected by case-tracing questionnaires.New infection was defined as a history of HIV negative testing within 1 year prior to confirmation,or a history of negative testing within 1.5 years with high-risk behavior within the last 1 year,or a first time CD4+T lymphocyte count of≥500/μL.Results A total of 1119 subjects were collected.Among the cases whose infection location could be determined,80.19%were infected in Nanjing.55.76%were newly infected among 1119 cases.Multivariate logistic regression analysis results showed that female,high school or technical secondary school or vocational school education,non-students,people who lived in Nanjing for more than half a years and people infected through homosexual sexual behavior were determined to be the relevant factors of local infection.Aged 24 years and younger,married,secondary school education or above,number of unmarried sexual partners in the 1 year before diagnosis was≥2,HIV antibody test before diagnosis,age of the first sexual behavior was≥18 years old were determined to be the relevant factors of new infection.Conclusion Newly reported HIV/AIDS in Nanjing from 2020 to June 2022 were mainly local infection and new infection.In the future,we should focus on local high-risk population intervention in Nanjing,and formulate detection strategies according to the characteristics of non-newly infected population,to further increase the proportion of early detection.