土壤-植物系统中抗生素抗性的传播过程与影响机制

Transmission and Influencing Mechanisms of Antibiotic Resistance in Soil-Plant System

土壤是抗生素抗性基因(antibiotic resistance genes,ARGs)的重要储存库,土壤-植物系统是ARGs从土壤向人体传播的主要渠道。因此,关注土壤-植物系统中抗生素抗性的传播过程与影响机制有助于系统性地了解抗生素抗性细菌(antibiotic resistant bacteria,ARB)、ARGs在土壤-植物中的迁移途径、传播规律和影响因素,可以为阻控抗生素抗性传播提供思路。本文总结了土壤中抗生素抗性的来源与演变机制,着重强调了抗生素抗性从土壤向植物的传播过程与影响因素,最后讨论了阻断ARGs在土壤-植物系统中传递的物理化学和生物控制技术,并提出了未来的研究方向,对遏制抗生素抗性传播、保障蔬菜作物安全与人体健康具有重要现实意义。

Soil is an important reservoir for antibiotic resistance genes(ARGs),while soil-plant system is a main channel for ARGs to spread from soil to human.Hence,it deserves great attention to the transmission of antibiotic resistance and influencing mechanisms in soil-plant system as it can assist to systematically understand the transmission routes and influencing factors of antibiotic resistant bacteria(ARB)and ARGs in the soil-plant system.The outcomes from this can provide guide for preventing and controlling the spread of antibiotic resistance.In this review,we summarized the origin and evolution mechanism of antibiotic resistance in soil by emphasizing the transmission processes and influencing factors of antibiotic resistance from soil to plant,then we discussed the physicochemical and biological control technologies to block the transmission of ARGs in the soil-plant system,and proposed the future research directions.It is of great significance to curb the spread of antibiotic resistance and ensure the safety of vegetable crops and human health.