宜宾市成人甲状旁腺激素参考区间的建立

Establishment of Reference Ranges for Adult Parathyroid Hormone in Yibin

目的:研究宜宾市健康成人甲状旁腺激素水平,建立成人甲状旁腺激素的参考区间,评价其与钙、镁、磷、尿素和肌酐的相关性。方法:采用雅培i2000化学发光分析仪测定EDTA抗凝血浆中宜宾市274名健康成人甲状旁腺激素水平,按性别为两组:男性组144人、女性组130人,采用两独立样本t检验比较两组的iPTH水平,以x±1.96 s建立血清iPTH的参考区间。结果:男性组与女性组成人甲状旁腺激素水平差异无统计学意义(P>0.05),成人甲状旁腺激素的iPTH参考值区间为28.28~114.80 pg/mL。iPTH与磷明显相关(P<0.05)。结论:初步建立了宜宾市成人EDTA抗凝血浆iPTH的参考区间,为评估其患者状态提供了依据。

Objective:To study the parathyroid hormone levels of healthy adults in Yibin,establish reference ranges for adult parathyroid hormone,and evaluate their association with calcium,magnesium,phosphorus,urea,and creatinine.Methods:Abbott i2000 chemiluminescence analyzer was used to determine the parathyroid hormone levels of EDTA anticoagulant plasma in 274 healthy Yibin adults,the t test of two independent samples was used to compare the levels of iPTH in two groups,and the reference interval of serum iPTH was established by X±1.96 s.Results:There was no significant difference in parathyroid hormone levels between male and female adults(P>0.05).The reference range of iPTH for adult parathyroid hormone was 28.28~114.80 pg/mL.iPTH was significantly correlated with P(P<0.05).Conclusion:The reference interval of iPTH of EDTA anticoagulant plasma in Yibin adults has been established,which provides a basis for evaluating the patient's status.