三酰甘油葡萄糖指数与腹膜透析患者腹主动脉钙化的相关性研究

Relationship between serum triglyceride glucose index and abdominal artery calcification in peritoneal dialysis patients

目的探讨腹膜透析(PD)患者三酰甘油葡萄糖(TyG)指数与腹主动脉钙化(AAC)之间的关系。方法选择2021年6月至2022年9月在温州市中心医院行维持性PD的84例患者。收集所有患者一般临床指标及实验室检查指标,计算TyG指数。所有患者行腹部侧位X线检查,根据检查结果分为钙化组51例和非钙化组33例。分析AAC与各临床指标之间的关系。结果与无钙化组比较,钙化组年龄、透析龄、IL-6、TyG指数及CRP差异均有统计学意义(均P<0.05)。二元logistic回归分析结果显示,年龄(OR=1.072,95%CI:1.015~1.132)、透析龄(OR=1.526,95%CI:1.133~2.056)、IL-6(OR=1.464,95%CI:1.023~2.093)和TyG指数(OR=5.422,95%CI:1.297~22.667)是PD患者发生AAC的独立危险因素(均P<0.05)。结论TyG指数与PD患者发生AAC有关,且是AAC的独立危险因素。

Objective To analyze the relationship between triglyceride glucose(TyG)index and abdominal artery calcification(AAC)in peritoneal dialysis(PD)patients.Methods A total of 84 patients who underwent PD in Wenzhou Central Hospital from June 2021 to September 2022 were recruited.The clinical data and laboratory results were collected and the TyG index was calculated.According to lateral abdomen x-ray examination,AAC was detected in 51 cases(AAC group)and did not detected in 33 cases(non-AAC group).The relationship between AAC and clinical indicators was analyzed.Results Age,years of dialysis,IL-6,TyG index and CRP were significantly higher in AAC group than in non-CAC group(all P<0.05).The binary logistic regression analysis showed that age(OR=1.072,95%CI:1.015-1.132),years of dialysis(OR=1.526,95%CI:1.133-2.056),IL-6(OR=1.464,95%CI:1.023-2.093)and TyG index(OR=5.422,95%CI:1.297-22.667)were the independent risk factors of AAC(all P<0.05).Conclusion TyG index is associated with AAC occurrence in PD patients,and is an independent risk factor for AAC.