基于CiteSpace分析国内外富血小板血浆在骨科领域的研究进展

Research progress of platelet-rich plasma in orthopaedics based on CiteSpace analysis

目的:基于CiteSpace软件,对富血小板血浆在国内外骨科领域中的运用进行图谱绘制、数据分析,总结并预测其在该领域的研究进展和发展趋势。方法:以中国知网、维普、万方、PubMed及Web of Science数据库为数据来源,筛选建库至2022年11月1日的富血小板血浆在骨科领域的相关文献,应用CiteSpace软件进行可视化分析,从年发文量、作者、关键词等方面进行讨论。结果:筛选得到国内三大数据库中富血小板血浆与骨科相关文献(核心期刊)共1089篇,PubMed数据库及Web of Science核心合集分别得到2568、1645篇。结果表明,国内外富血小板血浆在骨科领域的相关文献发文量逐年增加,研究中心主要集中在骨关节炎、骨组织工程、肌腱病、骨缺损等方面。结论:富血小板血浆未来的进一步应用,应侧重于向其“治疗疾病的生物分子学机制探讨”“注射规范与标准的建立”“骨关节炎临床疗效的精进”“与骨组织工程学的结合”等方向发展。

Objective:To map and analyze,on the basis of CiteSpace software,the use of platelet-rich plasma in the field of orthopedics at home and abroad,and to summarize its research progress and predict the development trend in this field.Methods:Using CNKI,VIP,Wanfang,PubMed and Web of Science databases as data sources,the relevant literature on platelet-rich plasma in the field of orthopedics from the date of database construction to November 1,2022 was screened,visualized and analyzed by CiteSpace software and discussed in terms of annual publication volume,authors and keywords.Results:A collection of 1089 papers related to platelet-rich plasma and orthopedics(core journals)from three major domestic databases were screened,and 2568 and 1645 papers were obtained from PubMed database and Web of Science core collection,respectively.The results suggested that the number of domestic and international publications had been increasing year by year,with the research focus mainly on osteoarthritis,bone tissue engineering,tendinopathy,and bone defects.Conclusion:The further application of platelet-rich plasma in the future should focus on the direction of“discussion on the biological molecular mechanism of treatment of diseases”,“establishment of injection norms and standards”,“improvement of clinical efficacy of osteoarthritis”and“combination with bone tissue engineering”.