某院Ⅱ类切口手术患者围手术期预防性使用抗菌药物的合理性分析

Analysis of Rationality for Perioperative Prophylactic Use of Antibacterial Dugs in Patients Undergoing Type Ⅱ Incision Surgery in a Hospital

目的:分析医院Ⅱ类切口手术患者围术期预防性使用抗菌药物的合理性,为临床抗菌药物的合理使用提供参考。方法:选取2020年5月—2022年5月于都县中医院收治的286例行Ⅱ类切口手术治疗患者作为研究对象,采集患者预防性使用抗菌药物的品种、用药时机、用药疗程等信息,并依据《抗菌药物临床应用指导原则》等权威文献评价用药的合理性。结果:286例Ⅱ类切口手术患者围术期均预防性使用了抗菌药物,其用药时机主要为术前0.5~2 h(251例,占87.76%),其用药疗程多为<48 h(248例,占86.71%),在品种选择上主要为头孢菌素类(253例次),此外有108例(占37.76%)患者存在2种抗菌药物联用的情况。结论:医院Ⅱ类切口手术患者围术期抗菌药物的预防使用整体较为合理,但在用药时机、用药疗程和品种选择上仍存在不少不合理情况,临床应当加强抗菌药物合理使用的学习和培训,以规范院内抗菌药物的使用。

Objective:To analyze the rationality of perioperative prophylactic use of antibacterial drugs in patients undergoing type Ⅱ incision surgery in the hospital,and provide reference for rational use of antibacterial drugs in the clinic.Methods:A total of 286 patients admitted to Yudu County Hospital of Traditional Chinese Medicine from May 2020 to May 2022 who underwent type II incision surgery were selected as the subjects,the information such as type,time of administration and course of treatment of the antibacterial drugs for prophylactic use was collected,and the rationality of drug use was evaluated according to the authoritative literature such as Guidelines for Clinical Use of Antibacterials.Results:All of the 286 patients who underwent type Ⅱ incision surgery were treated with antibacterial drugs prophylactically during the perioperative period,and the time of medication was mainly 0.5~2 h before operation(251 cases,87.76%),and the course of medication was mostly less than 48 h(248 cases,86.71%).For the type of drugs,they were mainly cephalosporins(253 cases),and two antibacterial drugs were concurrently used in 108 cases(37.76%).Conclusion:The prophylactic use of antibacterial drugs in the perioperative period of patients undergoing type II incision surgery in the hospital is generally reasonable,but there are many unreasonable situations in the timing of medication,course of medication and selection of drug type.Clinically it is necessary to strengthen the study and training of the rational use of antibacterial drugs,to standardize the use of antibacterial drugs in the hospital.