抗菌植物挥发油及其递送系统研究进展

Research Progress of Antibacterial Effects of Plant Volatile Oil and Their Delivery Systems

挥发油是从植物中获得的一种挥发性芳香物质,具有良好的抗菌活性,但当遇到氧气、光线及高温时,挥发油成分易挥发、易氧化分解及易变质。将水凝胶、微囊、脂质体、纳米乳、皮克林乳液和环糊精包合物等载药系统运用于挥发油组分时,可有效提高挥发油的稳定性、降低刺激性,同时可提高挥发油的抗菌作用及延长作用时间,扩大其临床应用范围。综述植物挥发油的提取方法、抗菌作用及载药系统的研究进展,以期为更合理有效地利用挥发油组分提供参考。

Volatile oil is a volatile aromatic substance obtained from plants and has good antibacterial activity.However,in the presence of oxygen,light and high temperature,the volatile oil components are easy to volatilize,oxidize,decompose and deteriorate.The application of hydrogel,microcapsule,liposome,nano-emulsion,Pickering emulsion and cyclodextrin inclusion compound in volatile oil components can effectively improve the stability and reduce irritation of volatile oil,while increasing the bacteriostatic effect of volatile oil,prolonging its time of action,and expanding the scope of its clinical application.This review summarizes the research progress of extraction methods,antibacterial effect and drug loading systems of plant volatile oil,so as to provide reference for the rational and effective utilization of volatileoil components.