双水平自主呼吸和时间控制通气模式无创呼吸机治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床效果

Clinical Effect of Dual-Level Spontaneous Breathing and Time Controlled Ventilation Mode Non-Invasive Ventilator in Treatment of Chronic Obstructive Pulmonary Disease Complicated with Type II Respiratory Failure

目的:分析慢性阻塞性肺疾病(COPD)伴Ⅱ型呼吸衰竭患者采用双水平自主呼吸和时间控制通气(ST)模式无创呼吸机进行治疗的临床效果。方法:选取2020年3月—2021年12月乌当区人民医院收治的78例COPD伴Ⅱ型呼吸衰竭患者作为研究对象,根据随机数字表法分为观察组与对照组,各39例。两组均给予无创呼吸机治疗,对照组采用持续气道正压通气模式,观察组采用ST通气模式。对比两组生命体征指标、血气分析指标、呼吸力学指标、治疗效果、不良反应发生情况。结果:治疗后,观察组收缩压、舒张压、心率水平低于对照组,血氧饱和度水平高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组动脉血氧分压、pH值、潮气量高于对照组,二氧化碳分压、呼吸频率低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P=0.022)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:COPD伴Ⅱ型呼吸衰竭患者采用ST模式无创呼吸机治疗,可有效改善患者的血气分析及通气状况,并提升治疗效果。

Objective:To analyze the clinical effect of dual-level spontaneous breathing and time controlled ventilation(ST)mode non-invasive ventilator in the treatment of chronic obstructive pulmonary disease(COPD)patients with type II respiratory failure.Methods:A total of 78 COPD patients with type II respiratory failure were selected from People's Hospital of Wudang District between March 2020 and December 2021,as the study subjects.They were divided into control group and observation group according to random number table method,with 39 cases in each group.Both groups were treated with non-invasive ventilator.The control group adopted continuous positive airway pressure mode.The observation group adopted ST ventilation mode.The vital sign indicators,blood gas analysis indicators,respiratory dynamics indicators,treatment effect and adverse reactions were compared between the two groups.Results:After treatment,the systolic blood pressure,diastolic blood pressure,and heart rate levels in the observation group were lower than those in the control group,and the blood oxygen saturation level in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the arterial partial pressure of oxygen,pH value and tidal volume in the observation group were higher than those in the control group,and the partial pressure of carbon dioxide and respiratory rate in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The overall effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.022).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:For COPD patients with type II respiratory failure,non-invasive ventilator in ST mode can effectively improve the blood gas analysis and ventilation status of patients,and improve the therapeutic effect.