摘要
金黄色葡萄球菌的耐药是其感染者不良预后的主要因素,在我国,儿童耐甲氧西林金黄色葡萄球菌(MRSA)的检出率逐年上升,尤以社区获得性MRSA(CA-MRSA)为主。现就CA-MRSA的分子学特征、耐药机制和耐药进展展开论述,分析近年我国儿童CA-MRSA的分子流行病学情况和耐药变迁,为儿童感染防控提供理论依据。
Antimicrobial resistance of Staphylococcus aureus is a main factor for the poor prognosis.In China,the detection rate of Methicillin-resistant Staphylococcus aureus(MRSA)in children is annually increasing,especially the community-acquired MRSA(CA-MRSA).This review discussed molecular characteristics,antimicrobial resistance mechanism and antimicrobial resistance progress of CA-MRSA,and analyzed recent molecular epidemiology and changes of drug resistance to CA-MRSA in children from China,thus providing theoretical basis for the prevention and control of CA-MRSA in children.
作者
杜青青
张泓
Du Qingqing;Zhang Hong(Department of Laboratory Medicine,Children's Hospital of Shanghai,Children's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200062,China)
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2023年第8期619-622,共4页
Chinese Journal of Applied Clinical Pediatrics
基金
上海市临床重点专科建设项目(shslczdzk06902)。
关键词
耐甲氧西林金黄色葡萄球菌
社区获得性
儿童
感染
分子流行病学
耐药性
Methicillin-resistant Staphylococcus aureus,community-acquired
Child
Infection
Molecular epidemiology
Antimicrobial resistance
