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血清IL-6、CRP水平与动脉瘤性蛛网膜下腔出血患者开颅夹闭术治疗预后的相关性

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摘要 目的:探讨血清白细胞介素-6(IL-6)、C反应蛋白(CRP)水平与动脉瘤性蛛网膜下腔出血(aSAH)患者开颅夹闭术治疗预后的相关性。方法:选取2018年8月-2020年10月在本院行开颅夹闭术治疗的95例aSAH患者作为研究对象。根据患者治疗后预后情况的不同,将患者分为预后良好组和预后不良组。设计基线资料收集表,收集患者的性别、年龄、发病至入院时间、IL-6、CRP水平等基线资料。患者入院当天,检测患者血清IL-6、CRP水平。分析对比两组的基线资料以及血清IL-6、CRP水平;分析血清IL-6、CRP水平与aSAH患者开颅夹闭术治疗预后的相关性。结果:95例aSAH患者开颅夹闭术后,预后不良34例(35.79%),预后良好61例(64.21%)。预后不良组血清IL-6、CRP水平高于预后良好组,差异有统计学意义(P<0.05);经Logistics回归分析,结果显示,血清IL-6、CRP高表达与aSAH患者开颅夹闭术后预后效果相关(OR>1,P<0.05)。结论:血清IL-6、CRP水平与aSAH患者开颅夹闭术治疗预后密切相关。
作者 高欢欢
出处 《四川生理科学杂志》 2023年第7期1261-1263,共3页 Sichuan Journal of Physiological Sciences
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