r-HuEPO配合鐵劑治療慢性腎衰貧血血透患者50例療效觀察

Observation of r-HuEPO with Iron Supplement for 50 Anemia Patient of CRF Performed Heamodialysis

目的:探討重組促紅細胞生成素(r-HuEOP)替代治療慢性腎衰(CRF)貧血血透患者的療效。方法:1997年1月~1998年7月間對50例CRF貧血血透患者,血透結束時皮下注射r-HuEPO 50 U/kg/次,配合鐵劑治療。結果:患者治療後HCT、Hb顯著上升(P<0.01),其中Hb上升30g/L佔30例;上升20g/L8例;上升10g/L9例,總有效率達94%。結論:r-HuEPO治療慢性腎衰貧血血透患詞重組促紅細胞生成素鐵劑慢性腎衰貧血血透者糾正貧血療效確切。治療前應注意補充鐵劑,應用r-HuEPO時注意副作用的發生。

Objective:To study the effect of recombinant human erythropoietin(r-HuEPO)replacement treatment for Anemic patients of chronic renal failure(CRF)performed heamodialysis.Methods:Fifty anemic patients of CRF under heamodialysis were treated with r-HuEPO and iron supplement in duration of Jan.1997 to Jul.1998.All patients were injected subcutanously with r-HuEPO in the fermination of heamodialysis.The Hb and HCT were assessed in the patients before and during r-HuEPO treatment.Result:HCT、Hb were significantly increased after management(p<0.01).Hb up to 30g/L in 30 cases;20g/L in 8 cases;1 Og/L in 9 cases.The efficiency was 94%.Conclusion:The effect of r-HuEPO with iron supplement being treated in the anemic patients of CRF performed heamodialysis is positive.It is better to pay more attention to iron supplement before treatment and prevent side effect of r-HuEPO.