我国中老年人肥胖对抑郁的影响

Effect of Obesity on Depression in Middle-aged and Elderly People in China

目的分析我国中老年人抑郁流行状况及不同类型肥胖对其影响。方法利用中国健康与养老追踪调查(CHARLS)数据库2015年随访数据,建立Logistic回归模型,分析全身性肥胖和腹型肥胖对抑郁的影响,并进行敏感性分析对结果加以验证。结果共纳入研究对象14171例,抑郁患病率为27.51%,全身性肥胖者共1905例,抑郁患病率为26.14%,腹型肥胖者共6655例,抑郁患病率为25.98%;不同性别、年龄、居住地、婚姻状况、吸烟、饮酒、社交状况、自评健康状况和慢性病人群的抑郁患病率比较,差异有统计学意义(P<0.05);随着BMI的增加,抑郁患病率呈下降趋势,腹型肥胖与非腹型肥胖抑郁患病率比较,差异有统计学意义(P<0.05);全身性肥胖中,超重组患抑郁的风险为偏瘦组的0.724倍(95%CI:0.606~0.865),肥胖组患抑郁的风险为偏瘦组的0.726倍(95%CI:0.595~0.884);腹型肥胖患抑郁的风险为非腹型肥胖组的0.764倍(95%CI:0.704~0.829)。结论随着肥胖的增加患抑郁的风险降低,在关注肥胖的同时,应重点关注体重快速减轻者的心理压力和情绪状态。

Objective To analyze the prevalence of depression in middle-aged and elderly people in China and the impact of different types of obesity on it.Methods Based on the follow-up data of China Health and Retirement Longitudinal Study(CHARLS)database in 2015,a Logistic regression model was established to analyze the effects of systemic obesity and abdominal obesity on depression,and sensitivity analysis was carried out to verify the results.Results A total of 14171 subjects were included in the study,and the prevalence of depression was 27.51%.There were 1905 patients with systemic obesity,and the prevalence of depression was 26.14%.There were 6655 patients with abdominal obesity,and the prevalence of depression was 25.98%.There were significant differences in the prevalence of depression among different gender,age,place of residence,marital status,smoking,drinking,social status,self-rated health status,and chronic diseases(P<0.05).With the increase of BMI,the prevalence of depression showed a downward trend,and there was a significant difference in the prevalence of depression between abdominal obesity and non-abdominal obesity(P<0.05).In general obesity,the risk of depression in overweight group was 0.724 times(95%CI:0.606-0.865)higher than that in underweight group,the risk of depression in obese group was 0.726 times(95%CI:0.595-0.884)higher than that in underweight group,and the risk of depression in abdominal obesity group was 0.764 times(95%CI:0.704-0.829)higher than that in non-abdominal obesity group.Conclusion With the increase of obesity,the risk of depression decreases.While focusing on obesity,we should pay attention to psychological stress and emotional state in people who lose weight rapidly.