摘要
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是常见的内分泌紊乱疾病,PCOS患者常因排卵障碍导致不孕。肥胖和胰岛素抵抗(insulin resistance,IR)在PCOS的发生发展中具有重要作用。有研究发现,PCOS患者呈现出一种慢性低水平炎症状态,这种炎症状态受到多种因素的影响,尤其是肥胖和胰岛素抵抗。该文对肥胖、胰岛素抵抗与炎症的关系,以及肥胖和胰岛素抵抗对PCOS患者炎症状态的影响进行了综述。
Polycystic ovary syndrome(PCOS)is a common endocrine disorder and often causes infertility due to ovulation dysfunction.Obesity and insulin resistance(IR)play important roles in the development of PCOS.It has been found that PCOS patients are often in a chronic low level inflammatory state,which is affected by a variety of factors,especially obesity and IR.The relationship between obesity,IR and inflammation,and the effect of obesity and IR on the low level inflammatory state of PCOS are reviewed in this paper.
作者
杨立
程玲
王志
黄冬梅
Yang Li;Cheng Ling;Wang Zhi(Institute of Integrated Traditional Chinese and Western Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,wuhan 430030,China;Department of Acupuncture and Moxibustion,East Hospital,Tongji University,Shanghai 200120,China)
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2023年第4期574-578,共5页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
基金
国家自然科学基金资助项目(No.81573787)。
关键词
多囊卵巢综合征
炎症
肥胖
胰岛素抵抗
polycystic ovary syndrome
inflammation
obesity
insulin resistance
