植物bHLH转录因子调控铁稳态的研究进展

Advances in the Regulation of Iron Homeostasis by bHLH Transcription Factors in Plant

铁是植物生长发育所必需的微量营养元素,生长在中性或碱性土壤中的植物普遍存在缺铁现象。而植物的正常生长发育需要保持体内铁的平衡,这种铁稳态在转录和转录后水平上都受到严格的调控。植物中铁稳态的调控网络由许多转录因子参与,其中碱性螺旋-环-螺旋(basic helix-loop helix,bHLH)家族的成员不可或缺。本文拟对植物中调控铁平衡的关键bHLH转录因子进行梳理汇总,对这些转录因子在植物生长发育中调节铁稳态的机制进行综述,以期为揭示植物铁稳态调节的研究提供理论基础。

Iron is an essential micronutrient for plant growth and development.Iron deficiency is widely existing in plants growing in neutral or alkaline soils.However,the normal growth and development of plants need to maintain the balance of iron,which is tightly regulated at both transcriptional and post-transcriptional levels.Many transcription factors are involved in the regulatory network of iron homeostasis in plants,among which members of the basic helix-loop helix(bHLH)family are essential for iron homeostasis.In this review,key bHLH transcription factors that regulate iron homeostasis are summarized,and the mechanisms by which these transcription factors regulate iron homeostasis in plant growth and development are reviewed,aiming to provide a theoretical basis to uncover the regulation of iron homeostasis in plants.