摘要
DNA甲基化能够在不改变DNA序列的情况下改变基因的表达和引起可变剪切等,进而改变细胞的表型甚至功能;并且这种修饰能够随着DNA的复制过程遗传给子代DNA,因而在植物体细胞突变过程发挥重要调控作用。虽然长期以无性繁殖为主,毛竹(Phyllostachys edulis)却存在丰富的自然突变类型,但是至今其遗传调控机制尚不清晰。本文综述了毛竹自然变异研究现状、植物DNA甲基化及其转录调控机制在植物发育过程中的研究进展,展望了DNA甲基化在解析毛竹自然变异现象的潜在应用,以期为竹类植物精准育种提供理论指导与技术支持。
DNA methylation can change gene expressions and cause variable splicing without any alterations in the DNA sequence,thus changing cell phenotype and even function;moreover,this modification can be transmitted to progeny DNA during the process of DNA replication and plays an important regulatory role in plant somatic mutation.Moso bamboo(Phyllostachys edulis)is mainly propagated by vegetative process,however,it has abundant natural mutation types,and the underlying genetic regulation mechanism is not clear so far.In this paper,we reviewed the advances of natural variation in Moso bamboo,DNA methylation and its transcriptional regulation in plant development,and prospected the potential application of DNA methylation in bamboo natural variation,aiming to provide theoretical guidance and technical support for accurate breeding of bamboo plants.
作者
李英
岳祥华
LI Ying;YUE Xiang-hua(Institute of Gene Science and Industrialization for Bamboo and Rattan Resources,International Center for Bamboo and Rattan,Beijing 100102;State Forestry and Grassland Administration,Beijing Key Laboratory on the Science and Technology of Bamboo and Rattan,International Center for Bamboo and Rattan,Beijing 100102;Sanya Research Base of International Centre for Bamboo and Rattan,Sanya 572000)
出处
《生物技术通报》
CAS
CSCD
北大核心
2023年第7期48-55,共8页
Biotechnology Bulletin
基金
国家自然科学基金项目(31901371)
国家重点研发计划(2021YFD2200503)。
关键词
表观转录调控
DNA甲基化
分化和发育
自然变异
竹类植物
epigenetic transcription regulation
DNA methylation
differentiation and development
natural variation
bamboo
