摘要
目的 :针对现有经颅磁刺激(transcranial magnetic stimulation,TMS)运动诱发电位(motor evoked potential,MEP)检测仪器体积大、难以便携的现状,设计一种结构简单的便携式TMS运动诱发电位检测系统。方法:该系统由MEP调理模块、MEP实时采集模块和PC数据接收端组成。其中,MEP调理模块包括仪表放大电路、滤波电路、二级放大电路、电平抬升电路以及电源电路;MEP实时采集模块包括基于STM32F407的模数转换器、串口通信模块和蓝牙模块;PC数据接收端基于Qt开发平台设计。结果:MEP调理模块的放大增益倍数在1 000~1 500范围内可调,共模抑制比约为110 dB,通频带为11~1 300 Hz;TMS运动诱发电位检测系统的采样率可达到10 kHz,能够实现MEP的检测。结论:TMS运动诱发电位检测系统体积小且便携,为基于TMS运动诱发电位的健康检测提供了技术支撑。
Objective To design a simple portable transcranial magnetic stimulation(TMS)motor evoked potential(MEP)detection system to solve problems of the existing instruments in size and portability.Methods The system consisted of a MEP conditioning module,a MEP real-time acquisition module and a PC data receiving terminal.The MEP conditioning module was composed of an instrument amplification circuit,a filtering circuit,a secondary amplifier circuit,a level lifting circuit and a power supply circuit;the MEP real-time acquisition module was made up of an analog-to-digital converter based on STM32F407,a serial communication module and a Bluetooth module;and the PC data receiving terminal was designed based on Qt development platform.Results The MEP conditioning circuit had an amplification gain multiplier adjustable from 1000 to 1500,a common mode rejection ratio of 110 dB and a passband of 10 to 1300 Hz;the TMS motor evoked potential detection system had a sampling rate up to 10 kHz.The designed TMS motor evoked potential detection system enabled the detection of MEP.Conclusion The TMS motor evoked potential detection system designed is small and portable,and provides technical support for the health examination based on TMS MEP.
作者
代宁宁
刘煦
靳静娜
逯迈
殷涛
DAI Ning-ning;LIU Xu;JIN Jing-na;LU Mai;YIN Tao(Key Laboratory of Optoelectronic Technology and Intelligent Control of Ministry of Education,Lanzhou Jiaotong University,Lanzhou 730070,China;Institute of Biomedical Engineering,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300192,China)
出处
《医疗卫生装备》
CAS
2023年第6期19-24,共6页
Chinese Medical Equipment Journal
基金
国家重点研发计划项目(2018YFC0115600)。
关键词
经颅磁刺激
运动诱发电位
MEP检测
蓝牙
transcranial magnetic stimulation
motor evoked potential
motor evoked potential detection
Bluetooth