椎体成形术在骨质疏松性椎体骨折治疗中的应用

Application of Vertebroplasty in the Treatment of Osteoporotic Vertebral Fracture

目的:分析椎体成形术在骨质疏松性椎体骨折治疗中的应用效果。方法:以我院2018年1月一2020年1月收治的骨质疏松椎体性骨折患者250例为本次研究对象,并以随机数字表法分为对照组和观察组,每组各125例,对照组患者采取保守措施治疗,观察组以椎体成形术治疗。统计对比2组治疗方案的应用价值。结果:(1)观察组患者临床疗效优良显著高于对照组(P<0.05),卧床时长、骨折端愈合时长及康复期间压疮、便秘、尿道感染、下肢深静脉血栓等并发症发生率均显著低于对照组(P<0.05);(2)2组患者治疗前骨代谢生化指标、骨密度水平、脊柱影像学表现、Barthel、ODI及SF-36评分评分无明显差异(P>0.05),但治疗后观察组患者骨代谢生化指标N-MID、BCP、骨密度水平、椎体前缘高度、椎体中线高度、椎体后缘高度、Barthel及SF-36评分均显著高于对照组(P<0.05),β-CTX及椎管侵占率、椎体压缩率、Cobb角等脊柱影像学表现指标及ODI评分则显著低于对照组(P<0.05)。结论:在骨质疏松性椎体骨折治疗中采取椎体成形术治疗,可取得理想治疗效果。

Objective:To analyze the effect of vertebroplasty in the treatment of osteoporotic vertebral fracture.Methods:250 patients with osteoporotic vertebral fracture admitted in our hospital from January 2018 to January 2020 were taken as the subjects of this study,and were randomly divided into the conventional group and the observation group(125 cases in each group).The patients in the conventional group were treated with conservative measures,while the patients in the observation group were treated with vertebroplasty.Statistically compare the application value of the two treatment schemes.Results:(1)The clinical efficacy of the observation group was significantly better than that of the conventional group(P;(2)There was no significant difference between the two groups in the biochemical indicators of bone metabolism,bone mineral density level,spinal imaging performance,Barthel,ODI and SF-36 scores before treatment(P>0.05),but after treatment,the biochemical indicators of bone metabolism N-MID,BGP,bone mineral density level,vertebral anterior edge height,vertebral midline height,vertebral posterior edge height,Barthel and SF-36 scores in the observation group were significantly higher than those in the conventional group(P<0.05),β-CTX,vertebral canal invasion rate,vertebral compression rate,Cobb angle and other spinal imaging indicators and ODI scores were significantly lower than those in the conventional group(P<0.05).Conclusion:In the treatment of osteoporotic vertebral fracture,vertebroplasty can achieve ideal therapeutic effect.