能谱CT最佳单能量成像结合低碘含量对比剂对肝细胞癌的诊断价值

The Diagnostic Value of CT Combined with Low Iodine Content Contrast in Hepatocellular Carcinoma

目的 探讨能谱CT最佳单能量成像(VMS)结合低碘含量对比剂诊断肝细胞癌(HCC)的价值。方法 选择84例疑似HCC患者为研究对象,将其中48例行能谱扫描低碘含量对比剂设为研究组,36例常规扫描高碘含量对比剂设为对照组。比较2组碘摄取量和CT剂量指数(CTDIvol)、有效剂量(ED)差异以及门静脉期、动脉期图像质量评分与客观评价结果差异。结果 84例患者中经手术证实HCC 69例,其中研究组37例,对照组32例。研究组碘摄取量和CTDIvol、ED较对照组低,有统计学差异(P<0.05);2组门静脉期和动脉期图像质量评分、最大强化率(CER)、信噪比(SNR)、相对噪声比(CNR)、噪声(SD)比较,无统计学差异(P>0.05)。结论 VMS结合低碘含量对比剂诊断HCC时可降低辐射剂量且所获得的图像符合诊断要求。

Objective To explore the value of optimal single energy imaging(VMS) combined with low iodine content contrast agent in the diagnosis of hepatocellular carcinoma(HCC).Methods 84 suspected HCC patients were selected as study subjects.48 low iodine contrasts were set as study group,and 36 conventional scanned high iodine contrasts were set as the control group.The difference in iodine intake and CT dose index(CTDIvol),effective dose(ED),and image quality score and objective evaluation results were compared between the 2 groups.Results Among 84 patients,HCC 69 was confirmed by surgery,including 37 in study group and 32 in control group,higher iodine intake and CTDIvol and ED than the control group(P<0.05),and portal and arterial image quality score(CER),signal/noise ratio(SNR)(relative noise ratio,noise(CNR)(SD)),without statistical difference(P>0.05).Conclusion VMS can reduce radiation dose in HCC with low iodine content contrast,and the images obtained can meet the diagnostic requirements.