肝细胞癌患者临床特征及肝切除术后其生存情况的模型评价

Clinical Characteristics of Hepatocellular Carcinoma Patients and Model Evaluation of Survival After Hepatectomy

目的分析肝切除术后HCC患者的临床特征和生存情况。方法搜集2004年至2018年美国SEER数据库中肝切除术后HCC患者的资料,并进行临床特征和预后分析。结果共纳入5049例患者,多因素分析显示年龄、肿瘤病理分化程度和肿瘤TNM分期是影响肝切除术后HCC患者的独立因素。结论年龄>70岁,GradeⅢ/Ⅳ期和T2、T3a/3b、T4和M1期的患者预后较差,能够作为独立危险因素预测肝切除术后HCC患者的预后,对于HCC患者应用肝切除术治疗可提高生存率。

Objective To analyze the clinical characteristics and survival of hepatocellular carcinoma(HCC)patients after hepatectomy.Methods The data of HCC patients after hepatectomy in the SEER database of the United States were collected,and the clinical characteristics and prognosis were analyzed.Results A total of 5049 patients were included.Multivariate analysis showed that age,tumor pathological differentiation and tumor TNM stage were independent factors affecting HCC patients after hepatectomy.Conclusion Patients with age >70 years,GradeⅢ/Ⅳ,and T2,T3a/3b,T4,and M1 have poor prognosis,and can be used as independent risk factors to predict the prognosis of HCC patients after hepatectomy.Hepatectomy treatment can improve survival rate for HCC patients.