肝移植后肝功能衰竭伴中性粒细胞内绿色小体1例

Liver failure with green neutrophilic inclusions after liver transplantation: a case report

该文报道1例44岁女性患者,以急性肝衰竭,肝性脑病收治入院。入院后予人工肝对症治疗,并于入院后第14天进行同种异体原位肝移植手术。患者入院后第68天,在外周血涂片中发现少量中性粒细胞胞浆中存在绿色小体。于入院后第71天因肝功能衰竭死亡。绿色小体是存在于瑞姬氏染色外周血涂片中性粒细胞细胞质中的亮绿色或蓝绿色包涵体,其出现与肝功能衰竭密切相关,是患者死亡的高危标志物。

We report a case of a 44-year-old female patient with acute liver failure and hepatic encephalopathy.The patient received artificial liver treatment and underwent allogeneic orthotopic liver transplantation at 14 days after admission.Laboratory examination reported a small number of green cytoplasmic inclusions in neutrophils on the peripheral blood smear at 68 days after admission.The patient eventually died of liver failure at 71 days after admission.Green inclusions are bright green or blue-green inclusions presented in the cytoplasm of neutrophils in Wright-Giemsa stained peripheral blood smears,and is associated with liver failure and high short-term mortality.