中西医结合治疗再生障碍性贫血

Treatment of aplastic anemia with combination of traditional Chinese and western medicine

再生障碍性贫血(AA)是一种骨髓造血功能衰竭性疾病,以外周血全血细胞减少为特征,存在感染和出血风险,威胁生命。西医治疗以异基因造血干细胞移植(allo-HSCT)、免疫抑制治疗(IST)和促造血治疗为主,中医上主张从肾论治。当前中西医结合治疗AA具备增效减毒等优势,是中国治疗AA的特色。文章对中西医结合治疗AA的研究进展做一评述。

Aplastic anaemia(AA)is a bone marrow haematopoietic failure disorder characterised by peripheral blood allogeneic cytopenia and a life-threatening risk of infection and bleeding.Western medicine treatment is based on allogeneic haematopoietic stem cell transplantation(allo-HSCT),immunosuppressive therapy(IST)and haematopoietic therapy,while Chinese medicine advocates a kidney-based approach.At present,the integrated treatment of Chinese and western medicine in AA has the advantages of increasing efficiency and reducing toxicity,which is the characteristic of AA treatment in China.The progress of research on the combined treatment of AA in Chinese and Western medicine is now reviewed.