正念干预对乳腺癌患者癌因性疲乏干预效果的Meta分析

Meta-analysis of Effect of Mindfulness-based Interventions on Cancer-related Fatigue in Breast Can-cer Patients

目的评价正念干预对乳腺癌患者癌因性疲乏(CRF)的干预效果。方法系统检索Web of Science、PubMed、Cochrane Library、Embase、中国生物医学文献数据库、维普、万方和中国知网数据库从建库至2021年5月23日公开发表的关于正念干预对乳腺癌患者癌因性疲乏的随机对照试验。采用RevMan 5.4进行Meta分析。结果最终纳入8篇文献,包括1042名受试者。结果表明,实施正念干预后,干预组患者的癌因性疲乏水平低于对照组[MD=-0.91,95%CI(-1.33,-0.49),P<0.01]。结论现有证据表明,正念干预是一种以生活方式为导向的非药物干预,可有效改善乳腺癌患者的癌因性疲乏。

Objective To evaluate the effect of mindfulness-based interventions on cancer-related fatigue(CRF)in breast cancer patients.Methods Web of Science,PubMed,Cochrane Library,Embase,CBMdisc,VIP,Wanfang Data and CNKI were systematically retrieved for the randomized controlled studies of mindfulness-based interventions on CRF in breast cancer patients from the establishment of the databases to May 23,2021.RevMan 5.4 was used for the Meta-analysis.Results A total of 8 articles were finally selected,including 1042 subjects.The results showed that the CRF level in the intervention group was lower than that in the control group after mindfulness-based interventions[MD=-0.91,95%CI(-1.33,-0.49),P<0.01].Conclusion The existing evidence shows that mindfulness-based interventions are lifestyle-oriented non-pharmacological interventions,which can effectively relieve CRF in breast cancer patients.