腹腔镜直肠癌根治术后远期预后及影响因素研究

Long-term prognosis and influencing factors after laparoscopic radical resection of rectal cancer

目的探讨腹腔镜直肠癌根治术后远期预后及影响因素。方法选择濮阳惠民医院2016年1月—2017年12月行腹腔镜直肠癌根治术患者102例,记录患者5年生存率,并查询分析影响其远期预后的危险因素。结果102例患者手术均顺利进行,术后随访5年,总生存患者74例,生存率72.55%。不同TNM分期、分化程度、肿瘤分型、术后并发症、神经侵犯、脉管侵犯、环周切缘患者远期预后不同,差异有统计学意义(P<0.05)。logistic回归分析结果显示,TNM分期、分化程度、肿瘤分型、神经侵犯、环周切缘均为影响腹腔镜直肠癌根治术后患者远期预后的危险因素(P<0.05)。结论腹腔镜直肠癌根治术后患者远期预后较差,影响其远期预后的因素众多,临床需加以重视。

Objective To explore the long-term prognosis and influencing factors after laparoscopic radical resec-tion of rectal cancer.Methods A total of 102 patients who underwent laparoscopic radical resection for rectal cancer from January 2016 to December 2017 were selected.The 5-year survival rate was recorded,and the risk factors affecting the long-term prognosis were investigated and analyzed.Results All the 102 patients were suc-cessfully operated and followed up for 5 years.The total survival rate was 72.55%(74 cases).The long-term prognosis of patients with different TNM stages,degrees of differentiation,tumor types,postoperative complica-tions,nerve invasion,vascular invasion and circumferential margin was different,and there were statistical differ-ences(P<0.05).Logistic regression analysis showed that TNM stage,differentiation degree,tumor type,nerve invasion and circumferential margin were all risk factors for long-term prognosis of patients after laparoscopic radi-cal resection of rectal cancer(P<0.05).Conclusion The long-term prognosis of patients after laparoscopic radical resection of rectal cancer is poor,and there are many factors affecting the long-term prognosis,which should be paid attention to in clinic.