摘要
免疫检查点抑制剂引起的暴发性1型糖尿病虽然发生率极低,但其可导致循环衰竭和致命性心律失常,死亡率高,是一种潜在的致命性疾病,临床需高度警惕。本文报道1例应用特瑞普利单抗治疗12周后出现暴发性1型糖尿病的病例,通过及时治疗病情好转,出院后一直给予胰岛素维持治疗。
The incidence rate of fulminant type 1 diabetes caused by immune checkpoint inhibitors is low,it is a potentially fatal disease that needs to be highly vigilant because it can lead to circulatory failure and fatal arrhythmia with high mortality.In this paper we report a case of fulminant type 1 diabetes after 12 weeks of treatment with toripalimab.Through timely treatment,the patient's condition improved and insulin maintenance treatment was continuously administered after discharge.
作者
王亚宁
张磊
赵鹏
姚民秀
徐倩
张方华
WANG Ya-ning;ZHANG Lei;ZHAO Peng;YAO Min-xiu;XU Qian;ZHANG Fang-hua(School of Clinical Medicine,Weifang Medical University,Shandong Weifang 261053,China;Department of Endocrinology,Qingdao Central Hospital Affiliated to Qingdao University,Shandong Qingdao 266042,China;Department of Clinical Laboratory,Qingdao Central Hospital Affiliated to Qingdao University,Shandong Qingdao 266042,China)
出处
《临床药物治疗杂志》
2023年第7期84-86,共3页
Clinical Medication Journal
