可持续蛋白纳米纤维及其功能因子递送研究进展

Research progress on sustainable protein nanofibers andtheir delivery of functional nutrients

随着世界人口的快速增长,人们对可持续食源蛋白质的需求日益增长。同时,对其营养与功能也提出了更高要求,如何在保障营养供给的同时,增强蛋白质的功能,提高其应用效率正成为食品工业所面临的重大挑战之一。过去十年,天然蛋白的功能因子递送功能一直是研究热点,然而,蛋白类功能载体具有一些应用难点,如蛋白分子对环境刺激敏感,载体结构稳定性差,递送效率和靶向性低下等。蛋白纳米纤维化改造可显著提升其载体性能,形成的淀粉样纤维具有特殊结构和良好的物化特性,其对营养小分子也表现出高亲和力,是营养功能因子的优良载体。该文重点阐述了可持续蛋白的纤维化过程以及淀粉样原纤维包埋递送功能因子的原理及途径,旨在为可持续蛋白形成的淀粉样纤维在食品工业中的高质量应用提供参考。

With the rapid growth of the world population,the demand for sustainable food source protein is increasing rapidly.At the same time,it also puts forward higher requirements for its nutrition and function.How to enhance the function of protein and improve its application efficiency while ensuring the supply of nutrition is becoming one of the major challenges facing the food industry.In the past decade,the functional factor delivery function of natural proteins has been a research hotspot and attracted wide attention.However,there are many difficulties in the application of protein functional carriers,such as the sensitivity of protein molecules to environmental stimuli,the poor stability of vector structures,and the low delivery efficiency and targeting.Protein nanofibrils modification can significantly improve the performance of its carrier.The formed amyloid fiber has a special structure and good physical and chemical properties,and it also shows a high affinity for nutritional small molecules.This article focused on the fibrosis process of sustainable protein and the principle and approach of amyloid fiber embedding and delivering functional factors to provide a reference for the high-quality application of amyloid fiber formed by sustainable protein in the food industry.