男性精神分裂症的指长比特征

Digit ratio in men with schizophrenia

目的 探讨指长比与宁夏汉族男性精神分裂症的关系。方法 采用体质测量法,数码相机提取216例男性受试者(正常对照:116例,精神分裂症患者:100例)指长照片,计算机图像分析软件(Image-Pro plus 6.0)标记解剖点并测量双手各指指长,比较对照组和患者组左手及右手2D∶3D、2D∶4D、2D∶5D、3D∶4D、3D∶5D、4D∶5D指长比均值的差异性,分析2D∶4D与患者组发病年龄的相关性。结果 除左手和右手3D∶4D外,患者组双手各指长比均显著高于对照组(双手2D∶4D和2D∶5D,右手3D∶5D,P均<0.001;双手2D∶3D和4D∶5D及左手3D∶5D,P均<0.01);与对照组相比(左手:1%,右手:1%),患者组(左手:6%,右手:7%)2D∶4D≥1的人数比例均显著增高(P<0.05);患者组2D∶4D均值与发病年龄无相关性(P>0.05)。结论 指长比与宁夏汉族男性精神分裂症的发生有关。

Objective To investigate the relationship between digit ratio and schizophrenia in men from Ningxia Han nationality.Methods Using anthropometry,digital camera was used to obtain finger photographs of both hands of 216 male subjects(normal control:116,schizophrenia patient:100).The anatomical points were marked and the length of each finger of both hands were measured by computer image analysis software(Image⁃Pro Plus 6.0).Differences of the mean digit ratio of left and right hand 2D∶3D,2D∶4D,2D∶5D,3D∶4D,3D∶5D,4D∶5D between the control group and the patient group were compared.The correlation between 2D∶4D and onset age in the patient group were analyzed.Results Except for left and right hand 3D∶4D,digit ratios in patient group were significantly higher than those in control group(2D∶4D and 3D∶5D in both hands,right hand 3D∶5D,pall<0.001;2D∶3D and 4D∶5D,left hand 3D∶5D,P<0.01).Compared with the control group(left hand:1%,right hand:1%),the percentage of 2D∶4D≥1 were significantly higher(P<0.05)in the patient group(left hand:6%,right hand:7%).There were no correlations between 2D∶4D mean value and onset age in patients group(P>0.05).Conclusion Digit ratio is related to the occurrence of schizophrenia in Ningxia Han male.