色谱-质谱联用的食品组学技术在食品科学研究中的应用

Applications of foodomics technology based on chromatography-mass spectrometry in food science research

食品组学是近年来新兴的利用基因组学、转录组学、蛋白质组学及代谢组学等系统生物学的分析思路和方法研究食品科学的一类技术,被广泛用于食品营养、食品安全及食品溯源等研究中。色谱与质谱的联用将色谱对复杂生物体系的高分离能力与质谱的高灵敏度、高分辨率、高选择性等优点相结合,具有分析速度快、定性定量结果准确、样品用量少等特点,是目前食品组学研究中一种强有力的检测技术。本文综述了基于色谱-质谱联用的食品组学技术的分析流程及该技术在食品营养品质、食品加工及贮藏、食品溯源及真伪鉴别、食品中农药残留、食品过敏原5个方面的应用,并提出了该技术的发展趋势及展望,旨在为食品科学与质量安全研究提供理论参考。

In recent years,foodomics is a kind of emerging technology that uses the analytical ideas and methods of genomics,transcriptomics,proteomics and metabolomics to study food science.It is widely applied in the studies of food nutrition,food safety and food traceability.The combination of chromatography and mass spectrometry combines the high separation ability of chromatography to complex biological systems with the advantages of high sensitivity,high resolution and high selectivity of mass spectrometry.It has the characteristics of fast analysis speed,accurate qualitative and quantitative results,and less sample consumption.It is a powerful detection technology in foodomics research.This paper summarized the analysis process of foodomics technology based on chromatography-mass spectrometry and the applications of this technology in food nutrition quality,food processing and storage,food traceability and authenticity identification,pesticide residues in food and food allergens,put forward the development trend and prospect of this technology,aiming to provide theoretical reference for food science and quality safety research.