帕金森病的神经影像纹理分析及影像组学研究进展

Research progress of neuroimaging texture analysis and radiomics in Parkinson's disease

纹理分析和影像组学是计算机辅助影像诊断的新兴领域,通过量化医学图像中肉眼难以评估的细微信息,可以克服视觉诊断的不足,辅助疾病的诊断及鉴别。帕金森病(Parkinson’s disease, PD)是一种复杂的进行性神经退行性疾病,发病率高而诊断准确性较低。近年来,多种基于纹理分析及影像组学的神经成像方法成为PD研究中的热点。本文就以上领域的研究现状及应用前景进行综述,旨在为PD的神经影像研究提供新思路,继而为PD的临床诊疗提供更精确的影像学支持。

Texture analysis and radiomics are emerging fields of computer-aided imaging diagnosis,which can overcome the deficiency of visual diagnosis and assist in the diagnosis and identification of diseases by quantifying subtle information in medical images that is difficult to assess with the naked eye.Parkinson's disease(PD)is a complex progressive neurodegenerative disease with a high prevalence and low diagnostic accuracy.In recent years,a variety of neuroimaging methods based on texture analysis and radiomics had become the focus of PD research.In this paper,the research status and application prospects of the above fields are reviewed,aiming at providing new ideas for neuroimaging research of PD,and then providing more accurate imaging support for clinical diagnosis and treatment of PD.